Propolis: chemical composition, biological properties and therapeutic activityM.C. Marcucci
Biological Chemistry Laboratory, Chemical Institute of Universidade Estadual de Campinas, CP 6154, cep 13081-970, Campinas, SP, Brazil
Abstract - The plant sources and chemical composition of propolis are reviewed. The chemical constituents that may be relevant to its biological and therapeutic activity are discussed. The cytotoxic activity and antimicrobial and pharmacological properties of propolis are presented. Propolis components, which cause allergy and are responsible for anticancer activity, eg, caffeic acid derivatives, are reported. The therapeutic efficacy of propolis in treating diseases caused by microorganisms is described. Some recent concepts about propolis and its use in medicine are presented.
Key words: propolis / phenolics / antimicrobial activity / toxicity / therapeutical activity