Free Access
Volume 34, Number 2, March-April 2003
Page(s) 139 - 145


  • Belzunces L.P., Lenfant C., Pasquale S.D., Colin M.E. (1994) In vivo and in vitro effects of wheat germ agglutinin and Bowman-Birk soybean trypsin inhibitor, two potential transgene prod- ucts, on midgut esterase and protease activities from Apis mellifera, Comp. Biochem. Physiol. 109 B, 63-69.
  • Broadway R.M., Duffy S.S. (1986) Plant proteinase inhibitors: mechanism of action and effect on the growth and digestive physiology of larval Heliothis zea and Spodoptera exigua, J. Insect Physiol. 32, 827-833.
  • Brødsgaard C.J., Hansen H., Ritter W. (2000) Progress of Paenibacillus larvae larvae infection in individually inoculated honey bee larvae reared singly in vitro, in micro colonies, or in full-size colonies, J. Apic. Res. 39, 19-27.
  • Brødsgaard C.J., Ritter W., Hansen H. (1998) Response of in vitro reared honey bee larvae to various doses of Paenibacillus larvae larvae spores, Apidolologie 29, 569-578.
  • Buchmann L.S., Nabham G.P. (1996) The forgotten pollinators, Island Press, Washington, USA.
  • Burgess E.P.J., Malone L.A., Christeller J.T. (1996) Effects of two proteinase inhibitors on the digestive enzymes and survival of honey bees (Apis mellifera), J. Insect Physiol. 42, 823-828.
  • Burgess E.P.J., Stevens P.S., Keen G.K., Laing W.A., Christeller J.T. (1991) Effects of protease inhibitors and dietary protein level on the black field cricket Teleogryllus commodus, Entomol. Exp. Appl. 61, 123-130.
  • Crailsheim K., Schneider L.H.W., Hrassnigg N., Buhlmann G., Brosch U., Gmeinbauer R., Schoffmann B. (1992) Pollen consumption and utilization in worker honeybees (Apis mellifera carnica): Dependence on individual age and function, J. Insect Physiol. 38, 409-419.
  • European and Mediterranean Plant Protection Organization (EPPO) (1999) Side effects on honeybees, EPPO Standards, Guideline for the efficacy evaluation of plant products, 1, 161-164.
  • EU (1990) Council Directive 90/220/EEC of 23 April 1990 on the deliberate release into the environment of genetically modified organisms, Official Journal L 117, 08/05/1990, 15-27, also available on line at: Dir.Eur.GB/Del.Rel./90.220/TC.html (consulted 3 Dec. 2002).
  • Free J.B. (1993) Insect pollination of crops, Academic Press, London, Great Britain.
  • Free J.B., Butler C.G. (1959) Bumblebees, Collins, London, Great Britain.
  • Girard C., Picard-Nizou A.L., Grallien E., Zaccomer B., Jouanin L., Pham-Delègue M.H. (1998) Effects of proteinase inhibitor ingestion on sur- vival, learning abilities and digestive proteinase of the honeybee, Transgenic Res. 7, 239-246.
  • Hilder A.H., Boulter D. (1999) Genetic engineering of crop plants for insect resistance - a critical review, Crop Prot. 18, 177-191.
  • Itenov K., Schøth F. (1993) Uniformity within race and genetic constitution of a population of the brown honeybee on the island of Læsø, SP-rapport 4, 35 p.
  • Jepson P.C., Croft B.C., Pratt G.E. (1994) Test systems to determine the ecological risks posed by toxin release from Bacillus thuringiensis genes in crop plants, Mol. Ecol. 3, 81-89.
  • Jouanin L., Bonadé-Bottin M., Girard C., Morrot G., Giband M. (1998) Transgenic plants for insect resistance, Plant Sci. 131, 1-11.
  • Lee S.I., Lee S.H., Koo J.C., Chun H.J., Lim C.O., Mun J.H., Song Y.H., Cho M.J. (1999) Soybean Kunitz trypsin inhibitor (SKTI) confers resistance to the brown planthopper (Nilaparvata lugens Stal) in transgene rice, Mol. Breed. 5, 1-9.
  • Malone L.A., Burgess E.P.J. (2000) Interference of proteinase inhibitors on non-target organisms, in: Michaud D. (Ed.), Recombinant Protease inhibi- tors in plants, Landes Bioscience, Georgetown, TX., USA, pp. 89-106.
  • Malone L.A., Pham-Delègue M.H. (2001) Effects of transgene products on honey bees (Apis mellifera) and bumble bees (Bombus sp.), Apidologie 32, 287-304.
  • Malone L.A., Giacon H.A., Burgess E.P.J., Maxwell J.Z., Christeller J.T., Laing W.A. (1995) Toxicity of trypsin endopeptidase inhibitors to honey bees (Hymenoptera: Apidae), J. Econ. Entomol. 88, 46-50.
  • Malone L.A., Burgess E.P.J., Christeller J.T., Gatehouse H.S. (1998) In vivo responses of honey bee midgut proteinases to two proteinase inhibitors from potato, J. Insect Physiol. 44, 141- 147.
  • Malone L.A., Burgess E.P.J., Stefanovic D., Gatehouse H.S. (2000) Effects of four proteinase inhibitors on the survival of worker bumblebees, Bombus terrestis L., Apidologie 31, 25-38.
  • Malone L.A., Tregidga E.L., Todd J.H., Burgess E.P.J., Philip B.A., Markwick N.P., Poulton J., Christeller J.T., Lester M.T., Gatehouse H.S. (2002) Effects of ingestion of a biotin-binding protein on adult and larval honey bees, Apidologie, 33, 447-458.
  • Marchetti S., Giordana A., Oliviere A.M., Fogher C., Delledonne M. (1994) Genetic engineering for insect resistance in potato: introduction of foreign proteinase-inhibitor genes, Potato Res. 37, 450- 451.
  • McGregor S.E. (1976) Insect pollination of cultivated plants, Agriculture Handbook No. 496, Agric. Res. Serv. USDA.
  • Moritz B., Crailsheim K. (1987) Physiology of pro- tein digestion in the mid gut of the honey bee, J. Insect Physiol. 33, 923-931.
  • Orr G.L., Strickland J.A., Walsh T.A. (1994) Inhibition of Diabrotica larval growth by a multicystatin from potato tubers, J. Insect Physiol. 40, 893-900.
  • Peng Y.-S.C., Mussen E., Fong A., Montague M.A., Tyler T. (1992) Effects of chlortetracycline of honey bee worker larvae reared in vitro, J. Invertebr. Pathol. 60, 127-133.
  • Pham-Delègue M.H., Girard C., Le Métayer M., Picard-Nizou A.L., Hennequet C., Pons O., Jouanin L. (2000) Long-term effects of soybean proteinase inhibitors on digestive enzymes, survival and learning abilities of honeybees, Entomol. Exp. Appl. 95, 21-29.
  • Rembold H., Kremer J.-P. (1980) Characterization of postembryonic developmental stages of the female castes of the honey bee, Apis mellifera L., Apidologie 11, 29-38.
  • Rembold H., Lackner B. (1981) Rearing of honeybee larvae in vitro: effect of yeast extract on queen differentiation, J. Apic. Res. 20, 165-171.
  • Ryan C.A. (1990) Proteinase inhibitors in plants: genes for improving defences against insect and pathogens, Annu. Rev. Phytopathol. 28, 939-943.
  • Schuler T.H., Poppy G.M., Kerry B.R., Denholm I. (1998) Insect-resistant transgenic plants, Trends Biotechnol. 16, 168-175.
  • Schuler T.H., Poppy G.M., Kerry B.R., Denholm I. (1999) Potential side effects of insect-resistant transgenic plants on arthropod natural enemies, Trends Biotechnol. 17, 210-216.
  • Svendsen O., Bertelsen I., Meyer I.-L. (1992) Identi- fication of honeybee subspecies (Apis mellifera mellifera versus Apis mellifera ligustica) by cubital index on the island of Læsø, Denmark, Tidsskr. Planteavl 96, 319-324.
  • Standifer L.N., MacDonald R.H., Levin M.D. (1970) Influence of the quality of protein in pollens and a pollen substitute on the development of the hypopharyngeal glands of honey bees, Ann. Entomol. Soc. Am. 63, 909-910.
  • USDA/APHIS (1991) User's guide for introducing genetically engineered plants and microorgan- isms, United States Department of Agriculture, Animal and Plant Health Inspection Service, Tech. Bull., 1783.
  • Wille H., Imdorf A., Bühlmann G., Kilchenmann V., Wille M. (1985) Beziehung zwischen Polleneintrag, Brutaufzucht und mittlerer Lebenserwartung der Arbeiderinnen in Bienenvölkern (Apis mellifera), Mitt. Schweiz. Entomol. Ges. 58, 205-214.
  • Wolfenbarger L.L., Phifer P.R. (2000) The ecological risks and benefits of genetically engineered plants, Science 290, 2088-2093.


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